EFSA review of Maximum Residue Limits for halquinol in pig tissues as set by JECFA

The European Commission requested the Food Safety Authority (EFSA) to review evaluation of halquinol by 85th and 88th meetings Joint FAO/WHO Expert Committee on Additives (JECFA) assess any other relevant scientific information in order establish whether there is ground for food safety concerns about maximum residues levels (MRLs) recommended JECFA. In several countries used as a veterinary drug pigs poultry enhance growth performance while this prohibited Union. JECFA derived an Acceptable daily intake (ADI) 0-0.2 mg/kg body weight, based histopathological changes associated with increase mean absolute relative kidney weights seen 1-year chronic toxicity study conducted rats has MRLs 500, 9000, 40 350 μg/kg liver, kidney, muscle skin+fat, respectively. Overall, EFSA considers that proposed are sufficiently low ensure consumers when exposed foodstuffs from treated pigs. However, due some limitations uncertainties toxicological database available, not position confirm ADI bw, set